Rebecca P. Seal, PhD Assistant Professor, Neurobiology
The Seal laboratory is focused on delineating the neural curcuitry that drives behvior normally and in disease. We aim to discover fundamental principals and mechanisms of the nervous system as well as identify novel treatment strategies for nervous system disorders. Our laboratory is curently studing: 1) peripheral and central pain circuits 2) peripheral and central auditory circuits 3) motor circuits affected by Parkinson's disease.
Experimental Approach: our laboratory uses mice as a model system and techniques such as virally-mediated DREADDs activation or inhibition of neurons, virally-mediated anterograde and retrograde circuit tracing, slice electrophysiology with optogentics, confocal and 2-photon microscopy, molecular biology, histology, biochemistry and behavior.
For more details visit the Seal Lab website at seallab.neurobio.pitt.edu